Clewell, Harvey J: search on Z-Library

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1

Improving Risk Assessment: Research Opportunities in Dose Response Modeling to Improve Risk Assessment

Zeise, Lauren, Hattis, Dale, Andersen, Mel, Bailer, A. John, Bayard, Steve, Chen, Chao, Clewell, Harvey, Conolly, Rory, Crump, Kenny, Dunson, David

Journal:

Human and Ecological Risk Assessment An International Journal

Year:

2002

Language:

english

File:

PDF, 212 KB

english, 2002

2

Uncertainty/Safety Factors in Health Risk Assessment: Opportunities for Improvement

Beck, Barbara D., Clewell III, Harvey J.

Journal:

Human and Ecological Risk Assessment An International Journal

Year:

2001

Language:

english

File:

PDF, 259 KB

english, 2001

3

Excretion of Di-2-ethylhexyl phthalate (DEHP) metabolites in urine is related to body mass index because of higher energy intake in the overweight and obese

Campbell, Jerry L., Yoon, Miyoung, Ward, Peyton L., Fromme, Hermann, Kessler, Winfried, Phillips, Martin B., Anderson, Warwick A., Clewell, Harvey J., Longnecker, Matthew P.

Journal:

Environment International

Year:

2018

Language:

english

File:

PDF, 537 KB

english, 2018

4

Evaluating opportunities for advancing the use of alternative methods in risk assessment through the development of fit-for-purpose in vitro assays

McMullen, Patrick D., Andersen, Melvin E., Cholewa, Brian, Clewell, Harvey J., Dunnick, Katie, Hartman, Jessica, Mansouri, Kamel, Minto, Melyssa S., Nicolas, Chantel I., Phillips, Martin, Slattery, Sc

Journal:

Toxicology in Vitro

Year:

2018

Language:

english

File:

PDF, 3.17 MB

english, 2018

5

Alginate-encapsulated primary human hepatocyte culture system to increase the accuracy of the predicted in vivo half-life of low clearance compounds

Yoon, Miyoung, Phillips, Martin B., Enders, Jeffrey R., Balbuena-Venancio, Pergentino, Billings, David, Norini, Rachel, Karsten, Ruby, Clewell, Harvey J.

Journal:

Drug Metabolism and Pharmacokinetics

Year:

2018

Language:

english

File:

PDF, 69 KB

english, 2018

6

Drop Formation and Evaporation of JP-4 Fuel Jettisoned from Aircraft

Good, R. Earl, Clewell III, Harvey J.

Journal:

Journal of Aircraft

Year:

1980

Language:

english

File:

PDF, 777 KB

english, 1980

7

Reverse dosimetry: interpreting trihalomethanes biomonitoring data using physiologically based pharmacokinetic modeling

Tan, Yu-Mei, Liao, Kai H, Clewell, Harvey J

Journal:

Journal of Exposure Science and Environmental Epidemiology

Year:

2006

Language:

english

File:

PDF, 266 KB

english, 2006

8

The application of PBPK models in estimating human brain tissue manganese concentrations

Ramoju, Siva P., Mattison, Donald R., Milton, Brittany, McGough, Doreen, Shilnikova, Natalia, Clewell, Harvey J., Yoon, Miyoung, Taylor, Michael D., Krewski, Daniel, Andersen, Melvin E.

Journal:

NeuroToxicology

Year:

2017

Language:

english

File:

PDF, 1.18 MB

english, 2017

9

Letter to the editor re: Cheng, YH., Chou, WC., Yang, YF. et al. Environ Sci Pollut Res (2017). https://doi.org/10.1007/s11356-017-0875-4

Travis, Kim Z, Clewell, Harvey J, Campbell, Jerry L, Hinderliter, Paul M

Journal:

Environmental Science and Pollution Research

Year:

2018

Language:

english

File:

PDF, 339 KB

english, 2018

10

Physiologically based pharmacokinetic (PBPK) modelling in risk assessment: Case study with pyrethroids

Mallick, Pankajini, Song, Gina, Efremenko, Alina Y, Pendse, Salil N, Creek, Moire R, Osimitz, Thomas G, Hines, Ronald N, Hinderliter, Paul, Clewell, Harvey J, Lake, Brian G, Yoon, Miyoung, Moreau, Mar

Journal:

Toxicological Sciences

Year:

2020

File:

PDF, 1.23 MB

2020

11

The impact of recent advances in research on arsenic cancer risk assessment

Gentry, P. Robinan, Clewell, Harvey J., Greene, Tracy B., Franzen, Allison C., Yager, Janice W.

Journal:

Regulatory Toxicology and Pharmacology

Year:

2014

Language:

english

File:

PDF, 1.23 MB

english, 2014

12

Limitations to Benzene Cancer Risk Assessment by Cox and Ricci

Kenny Crump, Bruce Allen, Harvey Clewell

Journal:

Year:

1993

Language:

english

File:

PDF, 127 KB

english, 1993

13

PBPK modelling of inter-individual variability in the pharmacokinetics of environmental chemicals

Frédéric Y. Bois, Masoud Jamei, Harvey J. Clewell

Journal:

Year:

2010

Language:

english

File:

PDF, 541 KB

english, 2010

14

PBTK modelling platforms and parameter estimation tools to enable animal-free risk assessment

Bessems, Jos G., Loizou, George, Krishnan, Kannan, Clewell, Harvey J., Bernasconi, Camilla, Bois, Frederic, Coecke, Sandra, Collnot, Eva-Maria, Diembeck, Walter, Farcal, Lucian Romeo, Geraets, Liesbet

Journal:

Regulatory Toxicology and Pharmacology

Year:

2014

Language:

english

File:

PDF, 926 KB

english, 2014

15

Dose-response for assessing the cancer risk of inorganic arsenic in drinking water: the scientific basis for use of a threshold approach

Tsuji, Joyce S., Chang, Ellen T., Gentry, P. Robinan, Clewell, Harvey J., Boffetta, Paolo, Cohen, Samuel M.

Journal:

Critical Reviews in Toxicology

Year:

2019

Language:

english

File:

PDF, 3.73 MB

english, 2019

16

Development of a physiologically based pharmacokinetic model of diisononyl phthalate (DiNP) in pregnant rat and human

Campbell, Jerry L., Otter, Rainer, Anderson, Warwick A., Longnecker, Matthew P., Clewell, Rebecca A., North, Colin, Clewell, Harvey J.

Journal:

Journal of Toxicology and Environmental Health Part A

Year:

2020

File:

PDF, 7.06 MB

2020

17

Incorporation of Pharmacokinetics in Noncancer Risk Assessment: Example with Chloropentafluorobenzene

Harvey J. Clewell III, Bruce M. Jarnot

Journal:

Year:

1994

Language:

english

File:

PDF, 1.03 MB

english, 1994

18

Dermal absorption of dihalomethane vapors

James N. McDougal, Gary W. Jepson, Harvey J. Clewell III, Melvin E. Andersen

Journal:

Toxicology and Applied Pharmacology

Year:

1985

Language:

english

File:

PDF, 769 KB

english, 1985

19

Physiologically based pharmacokinetic and pharmacodynamic model for the inhibition of acetylcholinesterase by diisopropyfluorophosphate

Jeffery M. Gearhart, Gary W. Jepson, Harvey J. Clewell III, Melvin E. Andersen, Rory B. Conolly

Journal:

Toxicology and Applied Pharmacology

Year:

1990

Language:

english

File:

PDF, 1.26 MB

english, 1990

20

Comparison and evaluation of pharmacokinetics of PFOA and PFOS in the adult rat using a physiologically based pharmacokinetic model

Anne E. Loccisano, Jerry L. Campbell Jr, John L. Butenhoff, Melvin E. Andersen, Harvey J. Clewell III

Journal:

Reproductive Toxicology

Year:

2012

Language:

english

File:

PDF, 901 KB

english, 2012

21

Response to Comments by Caldwell et al. on Article “Applying Mode-of-Action and Pharmacokinetic Considerations in Contemporary Cancer Risk Assessments: An Example with Trichloroethylene”

Clewell, Harvey J., Andersen, Melvin E.

Journal:

Critical Reviews in Toxicology

Year:

2006

Language:

english

File:

PDF, 67 KB

english, 2006

22

PHARMACODYNAMIC MODEL OF THE RAT ESTRUS CYCLE IN RELATION TO ENDOCRINE DISRUPTORS

Andersen, Melvin E., Clewell, Harvey J., Gearhart, Jeffrey, Allen, Bruce C., Barton, Hugh A.

Journal:

Journal of Toxicology and Environmental Health

Year:

1997

Language:

english

File:

PDF, 605 KB

english, 1997

23

Differential lymphatic versus portal vein uptake of the synthetic pyrethroids deltamethrin and cis-permethrin in rats

Higgins, Larry G., Chatham, Lynsey R., Tomczynski, Sara L., MacLeod, A. Kenneth, Moreau, Marjory, Clewell, Harvey J., Yoon, Miyoung, Creek, Moire R., Osimitz, Thomas G., Lake, Brian G.

Journal:

Year:

2020

File:

PDF, 687 KB

2020

24

Development of good modelling practice for physiologically based pharmacokinetic models for use in risk assessment: The first steps

George Loizou, Martin Spendiff, Hugh A. Barton, Jos Bessems, Frédéric Y. Bois, Michel Bouvier d’Yvoire, Harrie Buist, Harvey J. Clewell III, Bette Meek, Ursula Gundert-Remy, Gerhard Goerlitz, Walter S

Journal:

Regulatory Toxicology and Pharmacology

Year:

2008

Language:

english

File:

PDF, 196 KB

english, 2008

25

Integrating pathway-based transcriptomic data into quantitative chemical risk assessment: A five chemical case study

Russell S. Thomas, Harvey J. Clewell III, Bruce C. Allen, Longlong Yang, Eric Healy, Melvin E. Andersen

Journal:

Mutation Research/Genetic Toxicology and Environmental Mutagenesis

Year:

2012

Language:

english

File:

PDF, 835 KB

english, 2012

26

Introduction

Mattie, David R., Dodd, Darol E., Clewell, Harvey J.

Journal:

Toxicology Letters

Year:

1993

Language:

english

File:

PDF, 132 KB

english, 1993

27

Challenges in the application of quantitative approaches in risk assessment: a case study with di-(2-ethylhexyl)phthalate

Gentry, P. Robinan, Clewell, Harvey J., Clewell, Rebecca, Campbell, Jerry, Van Landingham, Cynthia, Shipp, Annette M.

Journal:

Critical Reviews in Toxicology

Year:

2011

Language:

english

File:

PDF, 2.51 MB

english, 2011

28

Application of Physiological Computational Fluid Dynamics Models to Predict Interspecies Nasal Dosimetry of Inhaled Acrolein

Schroeter, Jeffry D., Kimbell, Julia S., Gross, Elizabeth A., Willson, Gabrielle A., Dorman, David C., Tan, Yu-Mei, Clewell, Harvey J.

Journal:

Inhalation Toxicology

Year:

2008

Language:

english

File:

PDF, 7.06 MB

english, 2008

29

Perchlorate and Radioiodide Kinetics Across Life Stages in the Human: Using PBPK Models to Predict Dosimetry and Thyroid Inhibition and Sensitive Subpopulations Based on Developmental Stage

Clewell, Rebecca A., Merrill, Elaine A., Gearhart, Jeffery M., Robinson, Peter J., Sterner, Teresa R., Mattie, David R., Clewell, Harvey J.

Journal:

Journal of Toxicology and Environmental Health

Year:

2007

Language:

english

File:

PDF, 796 KB

english, 2007

30

Physiologically Based Pharmacokinetic Modeling of Arsenic in the Mouse

Gentry, P. Robinan, Covington, Tammie R., Mann, Sabine, Shipp, Annette M., Yager, Janice W., Clewell III, Harvey J.

Journal:

Journal of Toxicology and Environmental Health

Year:

2004

Language:

english

File:

PDF, 1019 KB

english, 2004

31

Pharmacokinetic bias analysis of the epidemiological associations between serum polybrominated diphenyl ether (BDE-47) and timing of menarche

Song, Gina, Peeples, Cody R., Yoon, Miyoung, Wu, Huali, Verner, Marc-André, Andersen, Melvin E., Clewell, Harvey J., Longnecker, Matthew P.

Journal:

Environmental Research

Year:

2016

Language:

english

File:

PDF, 551 KB

english, 2016

32

Physiologically Based Pharmacokinetic (PBPK) Modeling of Interstrain Variability in Trichloroethylene Metabolism in the Mouse

Chiu, Weihsueh A., Campbell, Jerry L., Clewell, Harvey J., Zhou, Yi-Hui, Wright, Fred A., Guyton, Kathryn Z., Rusyn, Ivan

Journal:

Environmental Health Perspectives

Year:

2014

Language:

english

File:

PDF, 1.16 MB

english, 2014

33

Revised assessment of cancer risk to dichloromethane II. Application of probabilistic methods to cancer risk determinations

Raymond M. David, Harvey J. Clewell, P. Robinan Gentry, Tammie R. Covington, David A. Morgott, Dale J. Marino

Journal:

Regulatory Toxicology and Pharmacology

Year:

2006

Language:

english

File:

PDF, 432 KB

english, 2006

34

An Alternative Exact Solution of the Two-Stage Clonal Growth Model of Cancer

Rudolf T. Hoogenveen, Harvey J. Clewell, Melvin E. Andemen, Wout Slob

Journal:

Year:

1999

Language:

english

File:

PDF, 446 KB

english, 1999

35

On the incorporation of chemical-specific information in risk assessment

Harvey J. Clewell III, Melvin E. Andersen, Bas J. Blaauboer

Journal:

Toxicology Letters

Year:

2008

Language:

english

File:

PDF, 591 KB

english, 2008

36

Review and Evaluation of the Potential Impact of Age- and Gender-Specific Pharmacokinetic Differences on Tissue Dosimetry

Clewell, Harvey J., Teeguarden, Justin, McDonald, Tracy, Sarangapani, Ramesh, Lawrence, Greg, Covington, Tammie, Gentry, Robinan, Shipp, Annette

Journal:

Critical Reviews in Toxicology

Year:

2002

Language:

english

File:

PDF, 1.02 MB

english, 2002

37

Refinement of the oral exposure description in the cyclic siloxane PBPK model for rats and humans: Implications for exposure assessment

Campbell, Jerry L., Andersen, Melvin E., Van Landingham, Cynthia, Gentry, Robinan, Jensen, Elke, Domoradzki, Jean Y., Clewell, Harvey J.

Journal:

Toxicology Letters

Year:

2017

Language:

english

File:

PDF, 3.14 MB

english, 2017

38

Population Life-course Exposure to Health Effects Model (PLETHEM): An R package for PBPK modeling

Pendse, Salil N., Efremenko, Alina, Eric Hack, C., Moreau, Marjory, Mallick, Pankajini, Dzierlenga, Michael, Nicolas, Chantel I., Yoon, Miyoung, Clewell, Harvey J., McMullen, Patrick D.

Journal:

Computational Toxicology

Year:

2019

File:

PDF, 1.37 MB

2019

39

The use of Markov chain Monte Carlo uncertainty analysis to support a Public Health Goal for perchloroethylene

Tammie R. Covington, P. Robinan Gentry, Cynthia B. Van Landingham, Melvin E. Andersen, Janet E. Kester, Harvey J. Clewell

Journal:

Regulatory Toxicology and Pharmacology

Year:

2007

Language:

english

File:

PDF, 292 KB

english, 2007

40

Revised assessment of cancer risk to dichloromethane: Part I Bayesian PBPK and dose–response modeling in mice

Dale J. Marino, Harvey J. Clewell, P. Robinan Gentry, Tammie R. Covington, C. Eric Hack, Raymond M. David, David A. Morgott

Journal:

Regulatory Toxicology and Pharmacology

Year:

2006

Language:

english

File:

PDF, 229 KB

english, 2006

41

Evaluation of the potential impact of pharmacokinetic differences on tissue dosimetry in offspring during pregnancy and lactation

P.Robinan Gentry, Tammie R. Covington, Harvey J. Clewell III

Journal:

Regulatory Toxicology and Pharmacology

Year:

2003

Language:

english

File:

PDF, 1.54 MB

english, 2003

42

Development of multi-route physiologically-based pharmacokinetic models for ethanol in the adult, pregnant, and neonatal rat

Martin, Sheppard A., McLanahan, Eva D., El-Masri, Hisham, LeFew, William R., Bushnell, Philip J., Boyes, William K., Choi, Kyoungju, Clewell, Harvey J., Campbell, Jerry L.

Journal:

Inhalation Toxicology

Year:

2012

Language:

english

File:

PDF, 1.54 MB

english, 2012

43

Use of in vitro data in developing a physiologically based pharmacokinetic model: Carbaryl as a case study

Yoon, Miyoung, Kedderis, Gregory L., Yan, Grace Zhixia, Clewell, Harvey J.

Journal:

Year:

2015

Language:

english

File:

PDF, 2.70 MB

english, 2015

44

PHYSIOLOGICALLY BASED PHARMACOKINETIC MODELING OF STYRENE AND STYRENE OXIDE RESPIRATORY-TRACT DOSIMETRY IN RODENTS AND HUMANS

Sarangapani, Ramesh, Teeguarden, Justin G., Cruzan, George, Clewell, Harvey J., Andersen, Melvin E.

Journal:

Inhalation Toxicology

Year:

2002

Language:

english

File:

PDF, 598 KB

english, 2002

45

COMPARING RESPIRATORY-TRACT AND HEPATIC EXPOSURE-DOSE RELATIONSHIPS FOR METABOLIZED INHALED VAPORS: A PHARMACOKINETIC ANALYSIS

Sarangapani, Ramesh, Clewell, Harvey J., Cruzan, George, Andersen, Melvin E.

Journal:

Inhalation Toxicology

Year:

2002

Language:

english

File:

PDF, 243 KB

english, 2002

46

Quantitative in vitro to in vivo extrapolation (QIVIVE): An essential element for in vitro-based risk assessment

Yoon, Miyoung, Blaauboer, Bas J., Clewell, Harvey J.

Journal:

Year:

2015

Language:

english

File:

PDF, 141 KB

english, 2015

47

Determination of Human Hepatic CYP2C8 and CYP1A2 Age-Dependent Expression to Support Human Health Risk Assessment for Early Ages

Song, Gina, Sun, Xueying, Hines, Ronald N., McCarver, D. Gail, Lake, Brian G., Osimitz, Thomas G., Creek, Moire R., Clewell, Harvey J., Yoon, Miyoung

Journal:

Drug Metabolism and Disposition

Year:

2017

Language:

english

File:

PDF, 717 KB

english, 2017

48

Dose-dependence of chemical carcinogenicity: Biological mechanisms for thresholds and implications for risk assessment

Clewell, Rebecca A., Thompson, Chad M., Clewell, Harvey J.

Journal:

Chemico-Biological Interactions

Year:

2019

Language:

english

File:

PDF, 2.21 MB

english, 2019

49

Development of a rat and human PBPK model for bromate and estimation of human equivalent concentrations in drinking water

Campbell, Jerry L., Bull, Richard J., Clewell, Harvey J.

Journal:

International Journal of Environmental Health Research

Year:

2019

File:

PDF, 1.50 MB

2019

50

Determination of an Occupational Exposure Guideline for Manganese Using the Benchmark Method

Harvey J. Clewell, Gregory A. Lawrence, Donald B. Calne, Kenny S. Crump

Journal:

Year:

2003

Language:

english

File:

PDF, 147 KB

english, 2003

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